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Results 1 to 25 of 2731

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New thiazole carboxamides as potent inhibitors of Akt kinasesSHAOHUA CHANG; ZHANG ZHANG; XIAOXI ZHUANG et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 2, pp 1208-1212, issn 0960-894X, 5 p.Article

Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor ModelsJIE LIN; SAMPATH, Deepak; LEE, Leslie B et al.Clinical cancer research (Print). 2013, Vol 19, Num 7, pp 1760-1772, issn 1078-0432, 13 p.Article

The Akt/PKB pathway : molecular target for cancer drug discoveryCHENG, Jin Q; LINDSLEY, Craig W; CHENG, George Z et al.Oncogene (Basingstoke). 2005, Vol 24, Num 50, pp 7482-7492, issn 0950-9232, 11 p.Article

The two TORCs and aktBHASKAR, Prashanth T; HAY, Nissim.Developmental cell. 2007, Vol 12, Num 4, pp 487-502, issn 1534-5807, 16 p.Article

Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cellsDE FRIAS, Mercè; IGLESIAS-SERRET, Daniel; COSIALLS, Ana M et al.Haematologica (Roma). 2009, Vol 94, Num 12, pp 1698-1707, issn 0390-6078, 10 p.Article

Minireview : AKT in thyroid tumorigenesis and progressionSHINOHARA, Motoo; YUN JAE CHUNG; SAJI, Motoyasu et al.Endocrinology (Philadelphia). 2007, Vol 148, Num 3, pp 942-947, issn 0013-7227, 6 p.Article

Akt/protein kinase BABRAHAM, Edward.Critical care medicine. 2005, Vol 33, Num 12, pp S420-S422, issn 0090-3493, SUPArticle

Identification of 3'-hydroxymelanetin and liquiritigenin as akt protein kinase inhibitorsYANG, Hye-Young; LEE, Hong-Sub; KO, Jong-Hee et al.Journal of microbiology and biotechnology. 2006, Vol 16, Num 9, pp 1384-1391, issn 1017-7825, 8 p.Article

Characterization of Akt Overexpression in MiaPaCa-2 Cells : Prohibitin Is an Akt Substrate both In Vitro and in CellsHAN, Edward Kyu-Ho; MCGONIGAL, Thomas; BUTLER, Chris et al.Anticancer research. 2008, Vol 28, Num 2A, pp 957-963, issn 0250-7005, 7 p.Article

Constitutively active Rheb induces oncogenic transformationJIANG, H; VOGT, P. K.Oncogene (Basingstoke). 2008, Vol 27, Num 43, pp 5729-5740, issn 0950-9232, 12 p.Article

Melatonin prevents the injury-induced decline of Akt/forkhead transcription factors phosphorylationKOH, Phil-Ok.Journal of pineal research. 2008, Vol 45, Num 2, pp 199-203, issn 0742-3098, 5 p.Article

Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytesROBINSON, Katherine A; BALL, Lauren E; BUSE, Maria G et al.American journal of physiology. Endocrinology and metabolism. 2007, Vol 55, Num 3, issn 0193-1849, E884-E890Article

Akt isoforms differentially regulate neutrophil functionsJIACHEN; HAIYANGTANG; HAY, Nissim et al.Blood. 2010, Vol 115, Num 21, pp 4237-4246, issn 0006-4971, 10 p.Article

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and RictorCHEN, Chia-Chen; JEON, Sang-Min; BHASKAR, Prashanth T et al.Developmental cell. 2010, Vol 18, Num 4, pp 592-604, issn 1534-5807, 13 p.Article

Girding for migratory cues: roles of the Akt substrate Girdin in cancer progression and angiogenesisLIANG WENG; ENOMOTO, Atsushi; ISHIDA-TAKAGISHI, Maki et al.Cancer science. 2010, Vol 101, Num 4, pp 836-842, issn 1347-9032, 7 p.Article

Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscleBLAAUW, Bert; MAMMUCARI, Cristina; TONIOLO, Luana et al.Human molecular genetics (Print). 2008, Vol 17, Num 23, pp 3686-3696, issn 0964-6906, 11 p.Article

Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondriaCHEN, Hang-Zi; ZHAO, Bi-Xing; ZHAO, Wen-Xiu et al.Carcinogenesis (New York. Print). 2008, Vol 29, Num 11, pp 2078-2088, issn 0143-3334, 11 p.Article

LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic ProteinsDIANSHENG ZHONG; XIUJU LIU; KHURI, Fadlo R et al.Cancer research (Chicago, Ill.). 2008, Vol 68, Num 18, pp 7270-7277, issn 0008-5472, 8 p.Article

The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-κB pathwayDELL'EVA, Raffaella; AMBROSINI, Claudia; MINGHELLI, Simona et al.Carcinogenesis (New York. Print). 2007, Vol 28, Num 2, pp 404-413, issn 0143-3334, 10 p.Article

Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of akt in polarized cellsTAKADA, Tappei; SUZUKI, Hiroshi; GOTOH, Yukiko et al.Drug metabolism and disposition. 2005, Vol 33, Num 7, pp 905-909, issn 0090-9556, 5 p.Article

Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignanciesCHAPUIS, N; TAMBURINI, J; GREEN, A. S et al.Leukemia. 2010, Vol 24, Num 10, pp 1686-1699, issn 0887-6924, 14 p.Article

Rictor is a novel target of p70 S6 kinase-1TREINS, C; WARNE, P. H; MAGNUSON, M. A et al.Oncogene (Basingstoke). 2010, Vol 29, Num 7, pp 1003-1016, issn 0950-9232, 14 p.Article

Negative cell cycle regulator 14-3-3σ stabilizes p27 Kip1 by inhibiting the activity of PKB/AktYANG, H; ZHANG, Y; ZHAO, R et al.Oncogene (Basingstoke). 2006, Vol 25, Num 33, pp 4585-4594, issn 0950-9232, 10 p.Article

eEF-2 Kinase Dictates Cross-Talk between Autophagy and Apoptosis Induced by Akt Inhibition, Thereby Modulating Cytotoxicity of Novel Akt Inhibitor MK-2206YAN CHENG; XINGCONG REN; YI ZHANG et al.Cancer research (Chicago, Ill.). 2011, Vol 71, Num 7, pp 2654-2663, issn 0008-5472, 10 p.Article

PKB/Akt―Dependent Regulation of Cell MotilityGONGDA XUE; HEMMINGS, Brian A.Journal of the National Cancer Institute. 2013, Vol 105, Num 6, pp 393-404, issn 0027-8874, 12 p.Article

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